In 1775, Daniel Boone leads settler families to Kentucky where their settlement is opposed by Indians as well as by others trying to claim the land first.
Following Dr. Frankenstein's death, his daughter and his lab assistant attempt to transplant the assistant's brain into the body of an unwitting servant.
Esther Blodgett catches the eye of alcoholic star Norman Maine, is given a test, and is caught up in the Hollywood glamor machine. A 5-star tearjerker.